---
title: Increased IFN-α activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive deficits
description: Increased IFN-α activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive deficits
---

<https://www.globallymealliance.org/research>

# [Increased IFN-α activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive deficits](https://www.globallymealliance.org/research/increased-ifn-α-activity-differential-antibody-response-patients-history-lyme-disease-persistent-cognitive-deficits)

 Written by [Global Lyme Alliance](https://www.globallymealliance.org/research/author/glalyme) | Feb 19, 2013 4:51:17 AM

Some patients treated for Lyme disease continue to suffer neurological symptoms. In these patients compared to healthy controls, there was increased interferon-α (IFNα) activity observed in the blood. IFNα is a cytokine, or chemical messenger, and together with the observation of elevated antibodies against B. burgdorferi and neural proteins, suggests an ongoing inflammatory response in these patients.

[View full post](https://www.globallymealliance.org/research/increased-ifn-α-activity-differential-antibody-response-patients-history-lyme-disease-persistent-cognitive-deficits)

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