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Lyme Disease Research

Global Lyme Alliance (GLA) has awarded over $16 million towards our Lyme and tick-borne disease research program to date. GLA-funded projects have led to unprecedented advances in such areas as prevention, diagnosis and treatment of tick-borne illnesses.

 

GLA-funded researchers—who were the first to prove the existence of the previously disputed chronic Lyme condition—have decoded the Lyme genome, discovered how the disease can survive antibiotic therapy, and now understand far more about what makes the Lyme bacterium different than any other type of infection. Learn more about our research.

 

New! Read Our Case for Support Documents

 

Screenshot 2023-01-31 at 1-41-44 PMPediatric Lyme Disease Case for Support

Protecting our most vulnerable patients.

Lyme is the fastest growing tick-borne illness in the US, with children being most at risk. While most children recover from the disease, today’s treatments are limited beyond the standard course of antibiotics which are not effective for about 3 out of every 10 patients. What's worse, most pediatric Lyme cases are missed. This can be tragic. Learn more in our case for support.

PROTECTING OUR KIDS

 

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Lyme and Mental Heath Case for Support

Global Lyme Alliance (GLA) is working to improve care for Lyme patients by funding research to find answers, give patients solutions to their problems, and raise awareness around the issue of Lyme and mental health. We need meaningful research efforts to understand this better, to raise awareness, and to treat patients better. Learn more about our groundbreaking research on Lyme and Mental Health.

LYME AND MENTAL HEALTH

 

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Diagnostics Case for Support

GLA seeks to transform the tick-borne disease diagnostics space by supporting innovative strategies that will better detect Lyme and other tick-borne diseases, preventing suffering from missed or delayed Lyme disease diagnosis. Recognizing the critical need for developing new and improved diagnostic tests. Learn more about the research we are supporting.

LYME DIAGNOSTIC CHALLENGES

Feel free to download and share our case for support documents. Questions? Email info@gla.org

 

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Research Partnerships

GLA has forged significant partnerships with the academic community who support research. Most notably, the organization partnered in 2007 with the Lyme Disease Association to fund and create the first research center for the study of persistent Lyme at Columbia University Medical Center in New York City.

For the past decade, GLA has funded innovative and promising research at top-tier universities across the United States, including Johns Hopkins University, Washington University in St Louis, Texas A&M, Northeastern University, University of Missouri, University of California San Francisco, University of Pennsylvania and Stony Brook University.

GLA announced a partnership with Ionica Sciences in October 2017 to develop an accurate Lyme disease diagnostic test.

Research Results

GLA has identified and funded groundbreaking research in the areas of diagnostics, therapeutics, and basic understanding of the Lyme bacterium:

  • Our researchers were the first to characterize chronic or post-treatment Lyme disease syndrome
  • GLA researchers sequenced the Borrelia burgdorferi genome of multiple strains; discovered how the bacteria can survive antibiotic therapy, and continue to document immune dysfunction in Lyme disease patients
  • Recent discoveries funded by GLA include the role cell wall-deficient forms, or L-forms, play in chronic bacterial infection, including Lyme disease
  • GLA Funded a groundbreaking study linking Lyme disease to psychiatric disorders

  • A drug discovery program funded by GLA at Northeastern University uncovers a novel antibiotic, Hygromycin A, that has the potential to cure early Lyme disease and prevent it from becoming a chronic condition
  • Learn more: See GLA's Timeline of Accomplishments or our comprehensive Research Report.

Patient Support Programs

GLA is here to support patients, caregivers, and loved ones of those who are living with Lyme and other tick-borne diseases. Our valuable resources will support you through every step in your journey.  Find a Lyme disease specialist, get information on financial support, access clinical trials, connect with a mentor for support, and access educational resources. Learn more about our programs.

Get Involved

There are many ways to get involved with GLA and make an impact in the fight against Lyme disease–from helping educate the community on Lyme and tick-borne diseases with our Ambassador program, to supporting GLA’s mission through fundraising or a donation. Learn more.

Stay up to date with GLA

For news, patient stories, and GLA's e-newsletter, click below.

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