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Science and Research posts

GLA Chief Scientific Officer Urges Support to Safeguard Lyme Research
August 21, 2025
Dear Friends & Supporters,
New Study Reveals Gut Impact of Lyme Disease
August 1, 2025
by Dr. Armin Alaedini, GLA Chief Scientific Officer, & Dr. Cara DeAngelis, Director of Research at Global Lyme Alliance
Evaluating the Ability of Hygromycin A to Reduce Lyme Disease Risk in Nature
July 22, 2025
Evaluating hygromycin A's potential to reduce Lyme disease by targeting white-footed mice. Efforts to curb Lyme disease often focus on preventing human exposure to ticks, but another strategy involves interrupting the bacteria's natural cycle between wild mice and ticks. In a new study published in ...
Why You Can Cross Mosquitoes Off Your Lyme Disease-Worry-List
June 24, 2025
A new study finds no evidence that mosquitoes can transmit Borrelia burgdorferi, the bacterium that causes Lyme disease. This study reinforces that ticks are the only proven source of infection. What did the study show?
Global Lyme Alliance Opens 2025 Funding Cycle for Lyme and Tick-Borne Disease Research
May 29, 2025
May 28, 2025 -- Global Lyme Alliance (GLA), the leading nonprofit dedicated to combatting Lyme disease through research, awareness, and patient support, is pleased to announce the opening of its 2025 research grant cycle. GLA prioritizes research that accelerates the development of innovative diagno...
GLA Grantee Publishes Two Pivotal Studies in Leading Journal
April 23, 2025
April 23, 2025--Global Lyme Alliance (GLA) is proud to announce that Dr. Brandon Jutras, a GLA grantee and researcher at Northwestern University, has published two pivotal studies in Science Translational Medicine, whichwere selected for the journal’s cover, highlighting the significance and innovat...
Dr. Jutras’ Lab Wins Phase 3 of LymeX Diagnostics Prize
January 21, 2025
Dr. Jutras' lab wins Phase 3 of LymeX Diagnostics Prize for the innovative Lyme disease test using monoclonal antibodies and immuno-PCR. The LymeX Diagnostics Prize, a competition to accelerate the development of diagnostics for Lyme disease, has announced the Phase 3 winners. Among them is the team...
GLA Research Update: New Insights Into Different Babesia Parasites
October 30, 2024
As tick-borne diseases spread, understanding diverse parasites is crucial for better diagnosis and treatment. A new GLA-funded study by Dr. Choukri Ben Mamoun reveals key differences between the parasites Babesia MO1 and Babesia divergens. These findings could lead to more targeted therapies for bab...
A Rapid Diagnostic Test Prototype for Lyme Disease Shows Promise with Faster Results
October 2, 2024
GLA Scientific Advisory Board Member, Paul Arnaboldi, Ph.D has been collaborating with multiple researchers to develop a rapid Lyme disease test that delivers results in 20 minutes from a small blood sample. This test could speed up diagnosis and treatment, but further development is needed before i...
Critical Analysis of a Babesia odocoilei and Bartonella Co-infection Study: Addressing Methodological Gaps and the Need for Validation
August 26, 2024
New research on co-infections of Babesia odocoilei and Bartonella spp. highlight the challenges in diagnosis and the importance of improved diagnostics in tick-borne diseases. Co-Infection Discovery
Facial Palsy: An Important Clue Pointing to Neurological Lyme disease
March 28, 2022
Global Lyme Alliance scientific advisory board member, Dr. Adriana Marques, led a study on Lyme neuroborreliosis patients, who take corticosteroids in addition to antibiotics, and whether or not the treatment had a negative effect on facial palsy recovery.
Tafenoquine and Atovaquone Combo Shows Promise in Babesiosis Treatment
January 5, 2024
Learn about a breakthrough in the treatment of babesiosis using a combination of tafenoquine and atovaquone. This innovative approach shows potential for complete cure and immune protection, according to recent research. The current treatments for babesiosis can come with severe side effects, the ri...
What is Rapid or Point-Of-Care Testing for Lyme Disease?
October 18, 2023
By Jane M. Caldwell, Ph.D. – Executive Director, Medavera Inc., Springfield, MO and Elizabeth Lee-Lewandrowski, Ph.D., MPH - Assistant Professor, Harvard Medical School, Department of Pathology, Massachusetts General Hospital, Boston
American Society for Microbiology Publishes Minireview, Research Funded by GLA
May 14, 2022
American Society for Microbiology (ASM) has over 30,000 members, including researchers, educators, and health professionals. ASM is one of the largest life science societies in the world. The minireview covers "Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatm...
Lyme Disease and Bell’s Palsy: New Considerations for Differential Diagnosis
March 28, 2022
Promising New Lyme Disease Antibiotic May Spare Microbiome
October 6, 2021
An exciting new finding by. Dr. Kim Lewis of Northeastern University gives hope that Lyme disease can be potentially treated without harming the microbiome Why is antibiotic treatment for Lyme disease often problematic? A significant side effect of treating Lyme disease is the disruption of the gut ...
Lyme Disease and Mental Disorders: It’s Not All in Your Head
July 29, 2021
A recent study in Denmark funded by Global Lyme Alliance analyzes patient data associated with Lyme disease and the impact it has on mental health Mental disorders are among the most poorly understood symptoms of Lyme disease. Early on, it was recognized that Lyme disease in late stages includes neu...
Meet the Researcher: Michael Eriksen Benros, M.D., Ph.D.
July 25, 2021
Michael Eriksen Benros, M.D., Ph.D. is professor and Head of Research at Mental Health Centre Copenhagen, Copenhagen University Hospital, Denmark. He received a two year grant from GLA for his study: Nationwide Cohort Studies Examining Psychiatric Disorders and Suicidal Behavior after Lyme disease.
Meet the Researcher: Shannon Delaney, M.D.
July 8, 2021
Shannon Delaney, M.D., is Director of Child and Adolescent Evaluation at the Lyme & Tick-borne Diseases Research Center, and Assistant Professor, Columbia University Vagelos College of Physicians and Surgeons. She is an expert in child and adult neuropsychiatry and infection-triggered neuropsych...
Borrelia miyamotoi: Hiding in Plain Sight?
May 22, 2021
GLA's Director of Research and Science, Dr. Mayla Hsu, discusses findings by Dr. Shannon Delaney, who suggests that Borrelia miyamotoi is an infectious trigger for chronic illness, closely resembling Lyme disease. What do we know about chronic illness following a Lyme disease diagnosis? We know that...
Meet the Researcher - George Aranjuez Ph.D.
March 29, 2021
George Aranjuez, Ph.D. is faculty research associate at University of Central Florida. His postdoctoral research was supported by a Deborah and Mark Blackman-GLA fellowship award. His most recent peer-reviewed articles, about the replication of Borrelia burgdorferi, appear here and here. Why did you...
Dendritic Cells: A Possible Pathway to Lyme Autoimmunity?
February 16, 2021
In the Covid-19 pandemic era, survival and recovery are on our minds. It’s become recognized that some patients recover quickly from Covid-19, but others may take months or possibly longer to feel better. Sound familiar? The Lyme disease community has a long experience with lingering, debilitating s...
Meet the Researcher: Maria Gutierrez-Hoffmann, Ph.D.
February 16, 2021
Maria Gutierrez-Hoffmann, Ph.D. is a scientist at the Food and Drug Administration in the Office of Pharmaceutical Manufacturing Assessment. As a postdoctoral fellow, her Lyme disease research was supported by GLA. Her most recent peer-reviewed publication is Borrelia burgdorferi-Induced Changes in ...
Lyme Disease Incidence: Even Greater Than Thought
February 5, 2021
POV by Timothy J. Sellati, Ph.D., Chief Scientific Officer, GLA How many people get Lyme disease every year? Precisely determining an annual incidence has been a challenge. Based upon a surveillance rather than a clinical definition, there is an ongoing discrepancy between Lyme disease cases reporte...
Meet the Researcher: Lise Nigrovic, M.D., M.P.H.
January 6, 2021
Meet the Researcher is a blog series to introduce GLA-funded Lyme disease researchers. Lise Nigrovic, M.D., M.P.H. is Associate Professor of Pediatrics and Emergency Medicine at Boston Children’s Hospital and Harvard Medical School in Boston, Massachusetts, USA.
An Innovative Approach To Understanding Pediatric Lyme Disease
December 28, 2020
by Mayla Hsu, Ph.D., Director of Research and Science, GLA
How Our Body ‘Sees’ Spirochetes Has Implications for Lyme Disease Severity and Novel Treatments
December 20, 2020
by Timothy J. Sellati, Ph.D., Chief Scientific Officer, GLA
The Similarities Between Post-COVID-19 and Lyme Disease
November 17, 2020
Tens of thousands of people in the U.S. have lingering illness following COVID-19, known as post-Covid “long haulers.” Why do some people recover relatively quickly from Lyme disease and Covid-19, and a significant number do not? by Mayla Hsu, Ph.D., Director of Research and Science, GLA
When Interpretation of Results Misses the Bull’s-eye
November 14, 2020
by Timothy J. Sellati, Ph.D., Chief Scientific Officer, GLA
Lyme Arthritis and Inflammation: Shut It Off!
September 23, 2020
A summary of 3 Lyme arthritis studies and how our immune system can fail to shut off when there’s an infection. by Mayla Hsu, Ph.D., Director of Research and Science, GLA
The need for an alternative to current antibody-based Lyme disease diagnostic tests
August 25, 2020
by Timothy J. Sellati, Ph.D., Chief Scientific Officer, Global Lyme Alliance
Global Lyme Alliance Announces New Research Grants to Address Critical Gaps in Lyme Disease Research
February 1, 2025
Pictured above: GLA Grantee, Brit Adler, MD, Assistant Professor of Medicine at Johns Hopkins University GLA announces new research grants to tackle critical gaps in Lyme disease research, including biobanking, pediatric Lyme disease, and chronic conditions. Global Lyme Alliance (GLA), the leading 5...
Global Lyme Alliance Names Dr. Armin Alaedini as Chief Scientific Officer
August 29, 2024
Dr. Armin Alaedini will join Global Lyme Alliance (GLA) on October 1, 2024. Dr. Cara DeAngelis will be promoted to Director of Research. Dr. Timothy Sellati transitions out of his role as CSO on August 29, 2024.