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Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs is yet unknown. The goal of this study was to examine gene transcription by B. burgdorferi following doxycycline treatment in an effort to identify both persister-associated genes and possible targets for antimicrobial intervention.

Published in Frontiers in Microbiology: https://www.frontiersin.org/articles/10.3389/fmicb.2019.00690/full
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31057493