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Variability in 2-tier Lyme disease test results according to the specific first-tier enzyme immunoassay (EIA) in children has not been examined rigorously. In this study, investigators paired results of clinical 2-tier Lyme disease tests to those of the C6 peptide EIA followed by supplemental immunoblotting (C6 2-tier test).

Published in The Journal of the Pediatric Infectious Diseases Society: https://academic.oup.com/jpids/advance-article-abstract/doi/10.1093/jpids/piy133/5359441?redirectedFrom=fulltext 
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30793167